Magnetically actuated artificial cilia for optimum mixing performance in microfluidics.
نویسندگان
چکیده
Contemporary lab-chip devices require efficient, high-performance mixing capability. A series of artificial cilia with embedded magnetic particles was fabricated to achieve precise flow manipulation through magnetically driven control. These fabricated structures were actuated in a homogeneous magnetic field generated by a built-in magnetic coil system for various beating cycles inside a microchannel. Three representative trajectories, namely, circular motion, back-and-forth oscillation, and a figure-of-eight pattern, of artificial cilia were designed and generated to mimic the motion of actual cilia. Homogeneous mixing of two highly viscous (>25 centipoise) dyed solutions by using the figure-of-eight trajectory achieved a mixing efficiency of approximately 86%. The underlying relationship between ciliated structures and the induced flow fields was further elucidated by performing a hydrodynamic analysis with micro-particle image velocimetry. In addition, a numerical modeling method which used a fluid structure interaction module was applied to provide quantitative 3D illustrations of induced flow patterns, including vortical structures and vortex core locations. The results reveal that both the magnitude and distribution of induced vortices primarily affect the mixing performance of two viscous flow streams. By using magnetically controlled artificial cilia along with the presented analytical paradigms, a new active flow mixing strategy was suggested to efficiently transport/agitate flows for microfluidics and biomedical applications.
منابع مشابه
Magnetically-actuated artificial cilia for microfluidic propulsion.
In this paper we quantitatively analyse the performance of magnetically-driven artificial cilia for lab-on-a-chip applications. The artificial cilia are fabricated using thin polymer films with embedded magnetic nano-particles and their deformation is studied under different external magnetic fields and flows. A coupled magneto-mechanical solid-fluid model that accurately captures the interacti...
متن کاملFluid transport at low Reynolds number with magnetically actuated artificial cilia.
By numerical modeling we investigate fluid transport in low-Reynolds-number flow achieved with a special elastic filament or artificIal cilium attached to a planar surface. The filament is made of superparamagnetic particles linked together by DNA double strands. An external magnetic field induces dipolar interactions between the beads of the filament which provides a convenient way of actuatin...
متن کاملSupporting Information Bio-inspired inner-motile photocatalyst film: a magnetically actuated artificial cilia photocatalyst
متن کامل
Magnetically actuated nanorod arrays as biomimetic cilia.
We present a procedure for producing high-aspect-ratio cantilevered micro- and nanorod arrays of a PDMS-ferrofluid composite material. The rods have been produced with diameters ranging from 200 nm to 1 mum and aspect ratios as high as 125. We demonstrate actuation of these superparamagnetic rod arrays with an externally applied magnetic field from a permanent magnet and compare this actuation ...
متن کاملArtificial cilia fabricated using magnetic fiber drawing generate substantial fluid flow
Microscopic hair-like structures, such as cilia, exist ubiquitously in nature and are used by various organisms for transportation purposes. Many efforts have been made to mimic the fluid pumping function of cilia, but most of the fabrication processes of these ‘‘artificial cilia’’ are tedious and expensive, hindering their practical applications. In this paper, an attractive and potentially co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Lab on a chip
دوره 13 14 شماره
صفحات -
تاریخ انتشار 2013